A feverish eight-year-old boy is taken to the physician with a runny nose and lethargy. The pediatrician finds that the youngster has a viral infection and does not require any special treatment after evaluating him. The mother inquires as to why an antibiotic is not required, and the doctor explains the distinctions between bacterial and viral illnesses. The immune system is made up of both cellular and humoral components that can create an efficient response to a variety of viral and bacterial diseases. The picture below depicts a portion of a normal lymph node. The structures indicated by the arrows are most likely to contain cells undergoing which of the following processes?

Question

A feverish eight-year-old boy is taken to the physician with a runny nose and lethargy. The pediatrician finds that the youngster has a viral infection and does not require any special treatment after evaluating him. The mother inquires as to why an antibiotic is not required, and the doctor explains the distinctions between bacterial and viral illnesses. The immune system is made up of both cellular and humoral components that can create an efficient response to a variety of viral and bacterial diseases. The picture below depicts a portion of a normal lymph node.  The structures indicated by the arrows are most likely to contain cells undergoing which of the following processes?

Quizplus · Accepted Answer

Eductional Objective: Initially, the predominant immune response to a novel antigen occurs in plasma cells that solely generate IgM. Later, in the germinal centers of lymph nodes, isotype switching occurs, requiring contact between the CD40 receptor on B-cells and the CD40 ligand (CD154) produced by activated T-cells. The primary serum immunoglobulin of the secondary reaction is IgG.

A Feverish Eight-Year-Old Boy Is Taken to the Physician with a Runny