A scientist is studying the structure of the sarcomere using skeletal muscle from an experimental animal. He creates monoclonal antibodies against a specific skeletal muscle protein and discovers that these antibodies prevent actin from attaching to structural support components within the sarcomere. The picture below depicts electron microscopy of a sarcomere. Which of the following labeled regions do these antibodies most likely bind?

Question

A scientist is studying the structure of the sarcomere using skeletal muscle from an experimental animal. He creates monoclonal antibodies against a specific skeletal muscle protein and discovers that these antibodies prevent actin from attaching to structural support components within the sarcomere. The picture below depicts electron microscopy of a sarcomere.  Which of the following labeled regions do these antibodies most likely bind?

Quizplus · Accepted Answer

Eductional Objective: The distance between two Z lines defines a single sarcomere. Thin filaments (actin) in the I band bind to structural proteins at the Z line, whereas thick filaments (myosin) in the A band bind to structural proteins at the M line.

A Scientist Is Studying the Structure of the Sarcomere Using