A 9-year-old child is brought to the office after experiencing facial and ocular puffiness for two days. About three weeks ago, the patient had antibiotic treatment for a rash on her leg. The temperature is 37.2 degrees Celsius (99 degrees Fahrenheit), and the blood pressure is 150/90 mm Hg. There is widespread edema but no rash on physical examination. Proteinuria and hematuria are shown by urinalysis. The following electron microscope picture represents this patient's illness process: The area marked by the white arrow most likely represents which of the following?

Question

A 9-year-old child is brought to the office after experiencing facial and ocular puffiness for two days. About three weeks ago, the patient had antibiotic treatment for a rash on her leg. The temperature is 37.2 degrees Celsius (99 degrees Fahrenheit), and the blood pressure is 150/90 mm Hg. There is widespread edema but no rash on physical examination. Proteinuria and hematuria are shown by urinalysis. The following electron microscope picture represents this patient's illness process:  The area marked by the white arrow most likely represents which of the following?

Quizplus · Accepted Answer

Eductional Objective: Poststreptococcal glomerulonephritis is an immune complex-mediated illness that develops 2-4 weeks after infection with group A beta-hemolytic Streptococcus. Immune complexes made up of IgG, IgM, and C3 are formed along the glomerular basement membrane and may be seen as enormous, dome-shaped, subepithelial, electron-dense deposits under electron microscopy.

A 9-Year-Old Child Is Brought to the Office After Experiencing