A 24-year-old guy visits the doctor complaining of hearing loss, dizziness, and tinnitus. Below is a contrast-enhanced, T1-weighted picture of his brain. This patient's condition is most likely associated with a mutation involving which of the following genes?

Question

A 24-year-old guy visits the doctor complaining of hearing loss, dizziness, and tinnitus. Below is a contrast-enhanced, T1-weighted picture of his brain.  This patient's condition is most likely associated with a mutation involving which of the following genes?

Quizplus · Accepted Answer

Eductional Objective: Bilateral tumors are visible at the cerebellopontine angle in the MRI scan above. The cerebellopontine angle is the location of the majority of intracranial schwannomas, which are connected to CN VIII. Acoustic neuromas are the name given to schwannomas in this area. The usual signs of an acoustic neuroma include tinnitus, vertigo, and hearing loss. In neurofibromatosis (NF) type 2, there might be bilateral auditory neuromas. NF-2 is different from NF-1 in that it affects the central nervous system and has less cutaneous symptoms.
Although they result from separate chromosomal alterations, both kinds of neurofibromatosis are autosomal dominant diseases. Below is a summary of how these 2 illnesses vary from one another.

A 24-Year-Old Guy Visits the Doctor Complaining of Hearing Loss