A 38-year-old woman comes to the physician because of a 1-month history of fatigue and pruritus. Physical examination shows skin excoriations and mild hepatomegaly. Laboratory results are as follows. The pathogenesis of this patient's disease process most closely resembles that of which of the following conditions?

Question

A 38-year-old woman comes to the physician because of a 1-month history of fatigue and pruritus. Physical examination shows skin excoriations and mild hepatomegaly.  Laboratory results are as follows.  The pathogenesis of this patient's disease process most closely resembles that of which of the following conditions?

Quizplus · Accepted Answer

Eductional Objective: Primary biliary cholangitis is a chronic autoimmune liver disease characterized by lymphocytic infiltrates and destruction of small and midsized intrahepatic bile ducts.  Similar findings are seen in hepatic graft versus host disease, highlighting the immunologic etiology of both disorders

A 38-Year-Old Woman Comes to the Physician Because of a 1-Month