A 55-year-old man comes to the office due to dull abdominal pain during last6 months ago. He also reports weight loss despite no dietary changes and feels fatigue all the time and anorexic. Vital signs are normal and physical examinations show no abnormalities. The liver function tests are normal and normal serum level of lipase. Upper endoscopy shows a gastric mass for which the patient underwent an uncomplicated total gastrectomy without any postoperative complications. The physician counsels the patient that he must receive lifelong administration of which of the following substances?

Question

A 55-year-old man comes to the office due to dull abdominal pain during last6 months ago. He also reports weight loss despite no dietary changes and feels fatigue all the time and anorexic. Vital signs are normal and physical examinations show no abnormalities. The liver function tests are normal and normal serum level of lipase. Upper endoscopy shows a gastric mass for which the patient underwent an uncomplicated total gastrectomy without any postoperative complications.  The physician counsels the patient that he must receive lifelong administration of which of the following substances?

Quizplus · Accepted Answer

Eductional Objective: Intrinsic factor (IF) is a glycoprotein that is normally secreted by parietal cells in the stomach and is necessary for the absorption of vitamin B₁₂ in the ileum. Patients who have undergone a total gastrectomy require lifelong vitamin B₁₂ supplementation due to inability to produce IF.

A 55-Year-Old Man Comes to the Office Due to Dull