A 7-year-old girl is brought to the physician because of generalized fatigue and facial puffiness. Four weeks ago, she was treated with topical mupirocin for a skin infection. Medical history is otherwise unremarkable and she takes no routine medications. Examination shows periorbital and 1+ pretibial edema bilaterally. The remainder of the examination shows no abnormalities. Urinalysis reveals: A biopsy image representative of this patient's disease process is shown below. Which of the following additional findings is most likely to be present in this patient?

Question

A 7-year-old girl is brought to the physician because of generalized fatigue and facial puffiness. Four weeks ago, she was treated with topical mupirocin for a skin infection. Medical history is otherwise unremarkable and she takes no routine medications. Examination shows periorbital and 1+ pretibial edema bilaterally. The remainder of the examination shows no abnormalities. Urinalysis reveals:  A biopsy image representative of this patient's disease process is shown below.  Which of the following additional findings is most likely to be present in this patient?

Quizplus · Accepted Answer

Eductional Objective: Poststreptococcal glomerulonephritis is the most common cause of nephritic syndrome in children.  Light microscopy demonstrates enlarged, hypercellular glomeruli.  Laboratory findings in poststreptococcal glomerulonephritis include elevated antistreptococcal antibodies (eg, antistreptolysin O, anti-DNase B) and decreased C3 and total complement levels.  C4 levels are usually normal.

A 7-Year-Old Girl Is Brought to the Physician Because of Generalized