A physician is conducting a study to evaluate effect of type II diabetes on kidney function in patients have recently been diagnosed with diabetes. An initial set of laboratory tests is obtained in newly enrolled patients to establish baseline renal function parameters The following measurements are taken from a 42-year-old male volunteer. Which of the following is the best estimate of the filtration fraction in this patient assuming a urine flow of 1.0 mL/min?

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Quizplus · Accepted Answer

Eductional Objective: The glomerular filtration rate (GFR) can be estimated by the inulin or creatinine clearance, while the renal plasma flow (RPF) is calculated using the para-aminohippuric acid clearance. The filtration fraction (FF = GFR / RPF) is the fraction of the RPF that is filtered across the glomerular capillaries into Bowman's space. It is usually equal to 20% in healthy individuals.

A Physician Is Conducting a Study to Evaluate Effect of Type