A researcher is conducting an animal study to assess the forces affect glomerular ultafiltration using a single nephron. He measures the hydrostatic pressure the glomerular capillary and Bowman space. Colloid osmotic pressure in the glomerular capillary is estimated using the difference in plasma protein concentration in the afferent and efferent arterioles. The glomerular surface is assumed to be functionally intact with negligible filtration of plasma proteins into the Bowman space. From the data obtained, net filtration pressure is calculated at 10 mm Hg. A substance is instilled into the renal artery, and measurements are repeated. The net filtration pressure after the intervention is 20 mm Hg. Which of the following substances was most likely used in this experiment?

Question

Quizplus · Accepted Answer

Eductional Objective: The net filtration pressure is a result of pressure gradients formed by Starling forces and is calculated by subtracting the oncotic pressure gradient from the hydrostatic pressure gradient. Angiotensin II preferentially constricts the efferent arteriole, resulting in an increased hydrostatic pressure gradient and an increased net filtration pressure

A Researcher Is Conducting an Animal Study to Assess the Forces