During physiological experiments on animal spinal fluid biomedical substances level after noxious stimuli. One of the substances increased as a result of the experiment is a pentapeptide with a strong affinity to delta- and mu-receptors. Which of the following substances is most likely to have a common molecular origin with the pentapeptide described above?

Question

Quizplus · Accepted Answer

Eductional Objective: Beta-endorphin is one endogenous opioid peptide that is derived from proopiomelanocortin (POMC).  POMC is a polypeptide precursor that goes through enzymatic cleavage and modification to produce not only beta-endorphins, but also ACTH and MSH.  The fact that beta-endorphin and ACTH are derived from the same precursor suggests that there may be a close physiological relationship between the stress axis and the opioid system.

During Physiological Experiments on Animal Spinal Fluid Biomedical Substances Level