What Phenotypic Features of Marfan Syndrome Are Responsible for the Major

What phenotypic features of Marfan syndrome are responsible for the major cause of morbidity and mortality associated with the syndrome?

A) Heart valve defects and weakening of the vessel wall of the aorta
B) Ocular disorders and an increased risk for retinal detachment
C) Skeletal abnormalities including arachnodactyly and dolichostenomelia
D) Pectus excavatum or pectus carinatum