According to the text, creativity in advertising is most often stifled by "killers", who are:

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The text specifically states that "client managers who don't recognize their own role in the killing" are the most common "killers" who stifle creativity in advertising. While other factors, such as shareholders or media buyers, may also play a role, the text does not suggest that they are as significant as client managers.

According to the Text, Creativity in Advertising Is Most Often