Matching
For each particular tumor antigen listed in questions 1-5, choose the class of tumor antigen (A-G) to which it belongs.
-E6 antigen
A)Product of a cellular oncogene
B)Overexpressed unmutated cellular proteins
C)Product of unmutated genes normally silent in most tissues
D)Overexpressed surface glycolipid
E)Oncofetal antigen
F)Tissue differentiation antigen
G)Product of an oncogenic virus

Question

Quizplus · Accepted Answer

Human papillomavirus (HPV) is the causative agent of cervical carcinoma, some skin cancers, and benign warts
HPV E6 and E7 are oncogenes whose protein products target and interfere with the function of the tumor suppressor genes p53 and Rb
HPV E6 and E7 are expressed by HPV-transformed tumor cells and stimulate host immune responses
These proteins have been used in experimental tumor vaccine protocols against cervical carcinoma.

Matching For Each Particular Tumor Antigen Listed in Questions 1-5, Choose