Which products would result from caspase cleavage of a protein with the amino acid sequence AVEELCSTWYYDLLCHMRTL?

Question

Quizplus · Accepted Answer

Caspase cleavage occurs between aspartic acid (D) and another amino acid. There are two aspartic acids in the given sequence, one after the amino acid LL and another after the amino acid L. Thus, cleavage can occur at either of these sites. If cleavage occurs after the amino acid LL, the resulting products would be AVEELCSTWYYD and LLCHMRTL. This corresponds to choice B. Cleavage after the amino acid L would result in the products AVEELCSTWYYDLLC and HMRTL, which is not one of the choices.

Which Products Would Result from Caspase Cleavage of a Protein