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Which Statement Regarding the Glucocorticoid Hypothesis of Depression Is False

Question 21

Multiple Choice

Which statement regarding the glucocorticoid hypothesis of depression is false?


A) The amygdala normally inhibits the hypothalamic-pituitary-adrenal (HPA) axis, whereas the hippocampus activates it.
B) High cortisol levels cause loss of cells and reduced neurogenesis in the hippocampus.
C) Behavioral characteristics of depression can be reduced in animals by administration of CRF.
D) ECT and antidepressant drugs may exert some of their clinical benefits by increasing CRF.

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