To study the role of the endogenous cannabinoids, scientists have used mice genetically engineered to lack _______ receptors, and these knockout mice show _______. A) CB₁; decreased anxiety B) CB₁ ; increased anxiety C) TRPV1; decreased anxiety D) TRPV1; increased anxiety

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The endogenous cannabinoids bind to cannabinoid receptors, therefore, mice genetically engineered to lack these receptors (CB₁) would not be able to respond to endogenous cannabinoids. Research shows that knockout mice lacking cannabinoid receptors exhibit increased anxiety-like behaviors, indicating the important role of endogenous cannabinoids in regulating anxiety.

To Study the Role of the Endogenous Cannabinoids, Scientists Have