You would expect that experimentally decreasing 2-AG breakdown in hippocampal glutamatergic neurons in mice would lead to which behavior?
A) Decrease in time spent sleeping
B) Increase in aggression
C) Decrease in in anxiety
D) Increase in fear

Question

Quizplus · Accepted Answer

2-AG is an endocannabinoid that can decrease anxiety when its breakdown is decreased, and the hippocampus is an area of the brain that is involved in anxiety regulation. Therefore, if 2-AG breakdown is decreased specifically in hippocampal glutamatergic neurons in mice, we would expect to see a decrease in anxiety-like behaviors.

You Would Expect That Experimentally Decreasing 2-AG Breakdown in Hippocampal