Which of the following is considered to be a glutamate co-agonist at the NMDA receptor site?
A) Ketamine
B) d-Serine
C) Magnesium
D) Aspartate

Question

Quizplus · Accepted Answer

d-Serine is considered to be a glutamate co-agonist at the NMDA receptor site. It binds to a different binding site on the NMDA receptor than glutamate, but it is required for proper activation of the receptor by glutamate. Ketamine is an NMDA receptor antagonist, magnesium is a voltage-dependent inhibitor of the receptor, and aspartate is an agonist at non-NMDA glutamate receptors.

Which of the Following Is Considered to Be a Glutamate