The choline transporter can be blocked by
A) vesamicol.
B) hemicholinium-3.
C) physostigmine.
D) pyridostigmine.

Question

Quizplus · Accepted Answer

Hemicholinium-3 is known to block the choline transporter, which inhibits the uptake of choline into the presynaptic neuron. This action prevents the synthesis of acetylcholine, a crucial neurotransmitter, thereby affecting cholinergic transmission. Vesamicol inhibits the vesicular acetylcholine transporter, not the choline transporter. Physostigmine and pyridostigmine are acetylcholinesterase inhibitors, which prevent the breakdown of acetylcholine, rather than affecting its synthesis or uptake.

The Choline Transporter Can Be Blocked by