Pyridostigmine can be used as an antidote to sarin because
A) pyridostigmine acts on ACh release, not on its breakdown by AChE.
B) temporary interactions between pyridostigmine and AChE prevent it from being permanently inactivated by sarin.
C) pyridostigmine inactivates sarin by interacting with its ACh binding site.
D) pyridostigmine prevents sarin from crossing the blood-brain barrier.

Question

Quizplus · Accepted Answer

Pyridostigmine does not directly counteract the effects of sarin. Instead, it works by temporarily binding to and inhibiting AChE, the enzyme that breaks down ACh. This leads to an increase in ACh levels in the body, which can help to counteract the effects of sarin. However, pyridostigmine itself can be toxic in high doses and must be used carefully under medical supervision.

Pyridostigmine Can Be Used as an Antidote to Sarin Because