A 47-Year-Old Woman Is Recovering from Surgery for Stage III

A 47-year-old woman is recovering from surgery for stage III ovarian cancer (spread to the peritoneal cavity but without parenchymal liver involvement) . Not all of the visible cancer could be resected; the largest residual tumor was 3 cm in diameter. Her performance status is excellent. She is interested in pursuing aggressive therapy and wishes to be treated as soon as possible in her local community. The proposed systemic therapy will involve cisplatin or carboplatin and paclitaxel. What further treatment is appropriate for this patient?

A) No further treatment beyond the proposed standard therapy
B) Another drug that has a different mechanism of action
C) Regional peritoneal therapy
D) High-dose therapy with peripheral or bone marrow stem cell rescue
E) A second-look laparotomy