Question 1

Persistent elevation of serum carcinoembryonic antigen following surgical resection of a carcinoma of the colon suggests:
A)a poorly differentiated neoplasm
B)a second cancer
C)cirrhosis
D)metastases
E)peritonitis

Accepted Answer

Persistent elevation of serum carcinoembryonic antigen (CEA) following surgical resection of colon carcinoma suggests the presence of metastases, as CEA is a tumor marker often used to monitor the treatment response and recurrence of colorectal cancer.

Question 2

In contrast to carcinoma of the right colon, carcinoma of the left colon tends to be associated with:
A)anemia
B)diverticulosis
C)malabsorption
D)obstruction
E)no symptoms

Accepted Answer

Carcinoma of the left colon often causes obstruction due to its smaller lumen and the tendency for tumors to grow in a circumferential pattern, leading to symptoms like constipation and abdominal pain.

Question 3

Which of the following lesions of the colon has the least tendency to undergo malignant transformation?
A)ulcerative colitis
B)juvenile polyp
C)villous adenoma
D)polyp of Gardner"s syndrome

Accepted Answer

Juvenile polyps are considered to have the least tendency to undergo malignant transformation compared to the other options listed. While conditions like ulcerative colitis, villous adenomas, and polyps associated with Gardner's syndrome have a higher risk of progressing to cancer, juvenile polyps are generally benign and have a very low risk of malignancy.

Question 4

Predisposes to adenocarcinoma:
A)Barrett"s esophagus
B)achalasia, esophagus
C)both
D)neither

Accepted Answer

Barrett's esophagus is a known risk factor for the development of esophageal adenocarcinoma due to the metaplastic changes in the esophageal lining. Achalasia is more commonly associated with squamous cell carcinoma of the esophagus.

Question 5

Predisposes to squamous cell carcinoma:
A)Barrett"s esophagus
B)achalasia, esophagus
C)both
D)neither

Accepted Answer

Achalasia is associated with an increased risk of squamous cell carcinoma of the esophagus, whereas Barrett's esophagus is associated with adenocarcinoma.

Quiz 7: Understanding Carcinoma and Other Neoplasms in the Gastrointestinal Tract: Part A

Persistent elevation of serum carcinoembryonic antigen following surgical resection of a carcinoma of the colon suggests:

In contrast to carcinoma of the right colon, carcinoma of the left colon tends to be associated with:

Which of the following lesions of the colon has the least tendency to undergo malignant transformation?

Predisposes to adenocarcinoma:

Predisposes to squamous cell carcinoma: