For previous patients, after the appropriate evaluation, the patient undergoes surgery. No intraoperative evidence of metastases is identified. Postoperatively, the pathology report reveals that the tumor is an adenocarcinoma invading into the pericolonic fat, with 2 involved lymph nodes. After the patient recovers from surgery, which of the following is the most appropriate next step in his management?

Question

Quizplus · Accepted Answer

Chemotherapy with a 5-fluorouracil (5-FU) based regimen is the most appropriate next step after surgery for a patient with colon cancer that has invaded into the pericolonic fat and with lymph node involvement. This indicates a more advanced stage of cancer (stage III), for which adjuvant chemotherapy has been shown to improve survival.

For Previous Patients, After the Appropriate Evaluation, the Patient Undergoes