A 57-year-old man is found to have a rectal mass 3 cm from the anal verge on digital rectal examination. Subsequent colonoscopy and biopsy confirm rectal adenocarcinoma. EUS examination demonstrates penetration of the tumor into, but not through, the muscularis propria, but shows significant perirectal lymph nodes. CT scan of chest/abdomen/pelvis demonstrates no metastases. The patient is staged as T2N1M0. What procedure should be attempted to remove the primary lesion in this patient?
A) Endoscopic mucosal resection (EMR) to remove the lesion
B) Endoscopic argon plasma coagulation (APC) therapy to cauterize and ablate the lesion
C) Surgical transanal excision of the lesion
D) Neo-adjuvant chemoradiation followed by transanal excision
E) Neo-adjuvant chemoradiation followed by abdominoperineal resection (APR)
Correct Answer:
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