Question 1

Which sentence is false in the merits of SEDDS?
A)Quick onset of action
B)Increase the Drug Dose.
C)Ease of manufacture & Scale up.
D)Improvement in oral bioavailability.

Accepted Answer

SEDDS (Self-Emulsifying Drug Delivery Systems) are designed to improve the solubility and oral bioavailability of poorly water-soluble drugs, not to increase the drug dose. Their merits include quick onset of action, ease of manufacture and scale-up, and improvement in oral bioavailability.

Question 2

Which one more convenient route of administration for SEDDS.
A)Oral
B)I.V
C)I.M
D)Skin

Accepted Answer

Self-emulsifying drug delivery systems (SEDDS) are most commonly designed for oral administration due to their ability to enhance the solubility and bioavailability of poorly water-soluble drugs. When ingested, SEDDS can form fine oil-in-water emulsions in the gastrointestinal tract, facilitating drug absorption.

Question 3

Which of the following false for in example of oil in SEDDS?
A)Corn oil
B)Olive oil
C)Sesame oil
D)Rice oil

Accepted Answer

Rice oil is not a common example used in Self-Emulsifying Drug Delivery Systems (SEDDS); typically, oils with higher solubilization capacity for lipophilic drugs, such as corn oil, olive oil, and sesame oil, are used.

Question 4

Which of the following is false for in examples of Surfactant in SEDDS?
A)Polysorbate 20
B)Polysorbate 80
C)Span 20
D)Sorbitan monooleate

Accepted Answer

Span 20 is not an example of a surfactant used in SEDDS.

Question 5

Which of the following is false for example of co-solvent?
A)Chloroform
B)Ethanol
C)Glycerin
D)Propylene glycol

Accepted Answer

Chloroform is not typically used as a co-solvent in pharmaceutical formulations due to its toxicity and potential for causing harm. Co-solvents like ethanol, glycerin, and propylene glycol are commonly used to enhance the solubility of drugs in formulations.

Question 6

Which are not Preferable route of administration for SEDDS?
A)Oral
B)Parenteral
C)Ophthalmic
D)Intra muscular

Accepted Answer

The answer of Which are not Preferable route of administration...

Question 7

Mucoadhesive drug delivery system is a part of ___________delivery system?
A)Control
B)Sustained
C)Prolong
D)Target

Accepted Answer

The answer of Mucoadhesive drug delivery system is a part...

Question 8

Drug loading capacity of MDDS.
A)Low
B)High
C)Very low
D)Medium

Accepted Answer

MDDS (Multifunctional Drug Delivery Systems) are designed to carry a significant amount of drug, hence they have a high drug loading capacity. This allows for efficient delivery of the therapeutic agent to the target site.

Question 9

Which theory use for the attractive electrostatic forces between glycoprotein Mucin network & the bio adhesive/ mucoadhesive material?
A)Electronic theory
B)Wetting theory
C)Adsorption theory
D)Diffusion theory

Accepted Answer

Electronic theory explains the attractive electrostatic forces between glycoprotein mucin networks and mucoadhesive materials, as it involves the interaction of electrical double layers.

Question 10

Which theory use for Physical entanglement of Mucin strands and flexible polymer chains.
A)Wetting theory
B)Adsorption theory
C)Diffusion theory
D)Fracture theory

Accepted Answer

Diffusion theory is used to explain the physical entanglement of mucin strands and flexible polymer chains, as it involves the movement and intermingling of molecules.

Question 11

Which route is not use for MDDS?
A)Nasal
B)Rectal
C)Oral
D)Buccal

Accepted Answer

Oral route is not typically used for Modified Drug Delivery Systems (MDDS) as these systems are designed for controlled release and targeted delivery, which is more effectively achieved through other routes like nasal, rectal, or buccal.

Question 12

Which polymers is not included in the semisynthetic class?
A)Chitosan
B)Gelatin
C)Pectin
D)Carbopol

Accepted Answer

Carbopol is a synthetic polymer, whereas chitosan, gelatin, and pectin are derived from natural sources and can be classified as semisynthetic.

Question 13

Which polymers is not soluble in water?
A)PVP
B)CMC
C)PEG
D)HPMC

Accepted Answer

Polyethylene glycol (PEG) is generally soluble in water, but at higher molecular weights, it becomes less soluble. However, among the options given, PEG is the least soluble compared to PVP (Polyvinylpyrrolidone), CMC (Carboxymethyl cellulose), and HPMC (Hydroxypropyl methylcellulose), which are more water-soluble.

Question 14

Which polymers are not having charge?
A)Starch
B)Amino dextran
C)Pectin
D)Sodium CMC

Accepted Answer

Starch is a natural polymer composed of glucose units and does not carry a charge, unlike the other options which are modified or inherently charged polymers.

Question 15

Which sentence is false in merits of MDDS?
A)Targeting & localization of the dosage form at a specific site
B)Painless administration
C)Low enzymatic activity & avoid of first pass metabolism
D)Some patient suffers unpleasant feeling

Accepted Answer

MDDS (Multiple Drug Delivery Systems) have several merits including targeting and localization of the dosage form at a specific site, painless administration, and reduced enzymatic activity which helps in avoiding first-pass metabolism. The statement that some patients suffer unpleasant feelings does not describe a merit of MDDS, making it the false statement among the options provided.

Question 16

Which are the following not including in semisolid dosage form in MDDS?
A)Gel & ointment
B)Tablet
C)Films
D)Patches

Accepted Answer

Tablets are not considered semisolid; they are solid dosage forms. Semisolid dosage forms in Modified Drug Delivery Systems (MDDS) include gels, ointments, films, and patches, which have a consistency between solid and liquid.

Question 17

What is the characteristics of mucoadhesive systems?
A)Release the drug along the entire length of GIT
B)Prolonged their residence in the GIT and release
C)Usage of bio adhesive polymer
D)Use of high or low density pellets

Accepted Answer

Mucoadhesive systems use bioadhesive polymers to prolong their residence in the GIT and release the drug along the entire length of GIT.

Question 18

Mucoadhesive are including in which drug delivery system?
A)Target drug delivery system
B)Control drug delivery system
C)Prolong drug delivery system
D)Diffusion drug delivery system

Accepted Answer

Mucoadhesive drug delivery systems are a type of controlled drug delivery system. They are designed to adhere to the mucosal surface of the body to deliver drugs at a controlled rate.

Question 19

Loading capacity of Mucoadhesive drug delivery system?
A)High
B)Poor
C)Medium
D)Very Poor

Accepted Answer

Mucoadhesive drug delivery systems generally have a poor loading capacity due to the limitations in the amount of drug that can be effectively bound to the mucoadhesive material without compromising its adhesive properties or the drug's bioavailability.

Question 20

Howmany water percentage are present in Mucoadhesive drug delivery system?
A)90 %
B)80%
C)95 %
D)101%

Accepted Answer

Mucoadhesive drug delivery systems typically have a high water content, around 95%, to ensure proper adhesion to mucosal surfaces.

Quiz 3: Drug Delivery Systems and Nanoparticles

Which sentence is false in the merits of SEDDS?

Which one more convenient route of administration for SEDDS.

Which of the following false for in example of oil in SEDDS?

Which of the following is false for in examples of Surfactant in SEDDS?

Which of the following is false for example of co-solvent?

Which are not Preferable route of administration for SEDDS?

Mucoadhesive drug delivery system is a part of ___________delivery system?

Drug loading capacity of MDDS.

Which theory use for the attractive electrostatic forces between glycoprotein Mucin network & the bio adhesive/ mucoadhesive material?

Which theory use for Physical entanglement of Mucin strands and flexible polymer chains.

Which route is not use for MDDS?

Which polymers is not included in the semisynthetic class?

Which polymers is not soluble in water?

Which polymers are not having charge?

Which sentence is false in merits of MDDS?

Which are the following not including in semisolid dosage form in MDDS?

What is the characteristics of mucoadhesive systems?

Mucoadhesive are including in which drug delivery system?

Loading capacity of Mucoadhesive drug delivery system?

Howmany water percentage are present in Mucoadhesive drug delivery system?