Which of the following statements is/are true about erythroblastosis fetalis?

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The cause is Rh factor incompatibility. Rh factor is the antigen found on RBCs of the Rh-positive individual. The mother, through a prior pregnancy, has become sensitized to the Rh factor (Rh isoimmunization) of the fetal RBCs. When sensitized maternal blood finds its way into fetal circulation, particularly during delivery, the antibodies in the mother's blood destroy the RBCs of the fetus (see Figures 2-48 and 2-49). If an Rh-negative woman has children with an Rh-positive man, some or all of the infants will be Rh positive. During pregnancy, blood from the Rh-positive fetus may move from fetal circulation into the mother's bloodstream, where it can stimulate the mother's body to form antibodies against the Rh factor. When sufficient quantities of the antibodies pass back into the infant's circulation, the antibodies can clump and destroy Rh-positive cells, causing the symptoms of erythroblastosis fetalis. Erythroblastosis fetalis is characterized by anemia, jaundice, kernicterus, and enlargement of the liver and spleen. In the most severe form, called hydrops fetalis, the fetus or infant is in great jeopardy because of extreme hemolysis. If the infant survives, the condition is marked by heart failure, edema, pulmonary congestion, lethargy, seizures, and mental retardation.

Which of the Following Statements Is/are True About Erythroblastosis Fetalis