Which of the following is (are) the result of insulin binding to its receptor?
I. MAPK activation via Erk, which regulates gene expression
II. PI3K activation, leading to an increase in glucose transport
III. PI3K activation, leading to increased protein synthesis
IV. Autophosphorylation

Question

Quizplus · Accepted Answer

Insulin binding to its receptor triggers several downstream effects, including autophosphorylation of the receptor, which is a crucial initial step. This leads to the activation of various signaling pathways, including the MAPK pathway (via Erk) that regulates gene expression, and the PI3K pathway, which is involved in increasing glucose transport into cells and promoting protein synthesis. Thus, all the listed outcomes are results of insulin binding to its receptor.

Which of the Following Is (Are) the Result of Insulin