In a series of laboratory experiments, you discover that reducing the pH of an enzymatic reaction reduces the biological activity of the enzyme to zero. When the change in pH is reversed the activity of the enzyme returns to normal. The best explanation for these observations is that at low pH the active site of the enzyme becomes non-functional because of a change in the enzyme's

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The change in enzyme activity due to pH alterations is most likely due to changes in the enzyme's tertiary structure. The tertiary structure involves the overall 3D shape of the enzyme, which is crucial for the functionality of its active site. Changes in pH can lead to alterations in hydrogen bonding and ionic interactions, affecting the enzyme's shape and thus its activity. When the pH is restored, the tertiary structure, and consequently the enzyme's activity, can return to normal.

In a Series of Laboratory Experiments, You Discover That Reducing