Defects in DNA repair are the underlying cause of several genetic diseases. Many of these diseases are characterized by a predisposition to cancer.
-Why are defects in DNA repair often associated with increases in cancer?
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Q1: Mutations are heritable changes in DNA. They
Q2: Gene mutations consist of changes in a
Q3: A suppressor mutation overrides the effect of
Q4: Mutation rate is the frequency with which
Q5: Spontaneous replication errors arise from altered base
Q6: Chemicals can produce mutations by a number
Q7: Mismatched bases and other DNA lesions are
Q8: Direct-repair mechanisms change altered nucleotides back into
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