You are examining a 33-year-old man whose chief complaints are that he has experienced recent weight loss and that he believes is due to the fact that he feels full after eating only a small amount of food. You determine that these symptoms are manifest due to a delay in the normal rate of gastric emptying. Given these findings, which of the following hormones is most likely to be excessively active in this patient?

Question

Quizplus · Accepted Answer

Cholecystokinin (CCK) is known to slow gastric emptying by stimulating the contraction of the pyloric sphincter and reducing gastric motility, which could explain the patient's symptoms of early satiety and weight loss.  The major control mechanism for gastric emptying involves duodenal gastric feedback, hormonal as well as neural. The major hormone involved in the inhibition of gastric emptying is cholecystokinin (CCK), which is released by fat and protein digestion products. Therefore, a reduction in gastric emptying would result from increased or excessive CCK activity resulting in rapid onset of satiety due to a feeling of fullness

You Are Examining a 33-Year-Old Man Whose Chief Complaints Are