You Are Examining the Characteristics of Monocyte Transmigration Through a Monolayer

You are examining the characteristics of monocyte transmigration through a monolayer of endothelial cells in a culture system. Your studies reveal that the addition of an experimental compound induces a significant increase in the rate of monocyte transmigration. This compound most likely induced the expression of which in the monolayer of endothelial cells?

A) E-selectin
B) endothelial-leukocyte adhesion molecule-1, ELAM-1
C) Intercellular adhesion molecule-1, ICAM-1
D) monocyte chemotactic protein-1, MCP-1
E) vascular cell adhesion molecule-1, VCAM-1