Question 1

The half-life of the drug is important to determine all of the following EXCEPT?

Accepted Answer

The answer of The half-life of the drug is important...

Question 2

The concentration of steady state (css) will increase when?

Accepted Answer

Increasing the rate of infusion, decreasing the rate of metabolism, and decreasing excretion all lead to an increase in the concentration of steady state (css) because they either increase the input or decrease the output of the drug in the body.

Question 3

To calculate half-life we use which the following formula?

Accepted Answer

The answer of To calculate half-life we use which the...

Question 4

The drug concentration between MEC and MTC is?

Accepted Answer

The therapeutic window is the range of drug concentrations between the minimum effective concentration (MEC) and the minimum toxic concentration (MTC).

Question 5

The correct sentence concerning parenteral administration is?

Accepted Answer

Parenteral administration bypasses the digestive system and delivers drugs directly into the bloodstream, leading to faster onset of action and potentially more rapid side effects compared to oral administration.

Question 6

Controlled-release tablets are formulated to release the drug in intestine to decrease the effect of gastric pH on it?

Accepted Answer

Controlled-release tablets are designed to release the drug at a controlled rate, often targeting the intestine to avoid degradation by gastric pH and to improve absorption.

Question 7

Which of the following may induce the hepatic microsomal P450 responsible for the metabolism of some drugs?

Accepted Answer

Smoking, ethanol, and a high protein diet can all induce hepatic microsomal P450 enzymes, affecting drug metabolism.

Question 8

Drug X produces maximal contraction of cardiac muscle in a manner similar to epinephrine. Drug X is considered to be a/an?

Accepted Answer

Drug X produces maximal contraction similar to epinephrine, indicating it fully activates the receptor, classifying it as an agonist.

Question 9

All of the following concerning the blood-brain barrier (BBB) and the passage of drugs from the systemic circulation to cerebrospinal fluid (CSF) is true EXCEPT?

Accepted Answer

The answer of All of the following concerning the blood-brain...

Question 10

Drug concentration at the receptor site is influenced by all of the following except?

Accepted Answer

Allosteric interaction with microsomal enzymes affects drug metabolism but does not directly influence drug concentration at the receptor site.

Quiz 1: Understanding Pharmacokinetics and Drug Administration