When Comparing the Administration of Local Anesthesia in a 4-Year-Old

When comparing the administration of local anesthesia in a 4-year-old healthy boy to an 80-year-old man with a history of hypertension, cirrhosis, and diabetes, which of the following statements is likely to be true?

A) Liver failure is less likely a problem in the older patient
B) Maximal dose of anesthetic must be calculated
C) Older patients require higher doses of anesthetic
D) Older patients will have a better response to anesthetic
E) Younger patients will have a better response to anesthetic