An IgG2 subclass response is important for proper immunization with the meningococcal vaccine because:

Question

Quizplus · Accepted Answer

The organisms that cause meningitis have a carbohydrate-rich capsule, and IgG2 subclasses respond strongly to carbohydrate antigens. Therefore, the IgG2 response provides a stronger primary response, which will make memory cells to provide a stronger secondary response in case of subsequent exposure to the organism.

An IgG2 Subclass Response Is Important for Proper Immunization with the Meningococcal