What causes increased thirst in patients with untreated or uncontrolled diabetes?
A) Glucose in the kidney changes pH, which alters fluid balance.
B) Glucose in the kidney damages cells that control water movement.
C) Glucose in the kidney changes osmolarity, which increases water output.
D) Glucose in the kidney damages the glomerulus and too much water is filtered.

Question

Quizplus · Accepted Answer

The high levels of glucose in the blood spill over into the urine, and the change in osmotic pressure causes water to move out of cells and into the lumen of the nephron. This water is eliminated in the urine, and the change in osmolarity in the kidney triggers release of hormones that signal thirst to the brain.

What Causes Increased Thirst in Patients with Untreated or Uncontrolled