What is the outcome of matrilysin cleaving FasL from an activated T cell?
A) Soluble FasL is degraded and the activated T cell survives.
B) Soluble FasL binds to Fas and triggers the death of the activated T cell.
C) Soluble FasL binds to Fas and triggers the death of the regulatory T cell.
D) Soluble FasL is disseminated and causes widespread cell death in both immune cells and infected host cells.

Question

Quizplus · Accepted Answer

Matrilysin cleaves FasL from the activated T cell, and the soluble FasL binds to Fas on the same cell, causing death of the activated T cell. This matrilysin/Fas:FasL pathway serves an immune regulator function and assists in downregulating the immune response. T regulatory cells are not involved in this pathway.

What Is the Outcome of Matrilysin Cleaving FasL from an Activated