Twenty-five years ago,when Oshima and colleagues discovered that a mutation in the GAL4 gene led to the inability to synthesize all five enzymes required for galactose catabolism (breakdown),they couldn't be blamed for wanting to apply a bacterial model to explain this finding.What they expected,but did not find,was _____.
A)for all five genes to constitute an operon
B)five widely separated genes,each containing a GAL4 binding site in its regulatory region
C)for chromatin decondensation to play an important role in regulating the genes of galactose catabolism
D)for transcription to be important in regulating the genes of galactose catabolism

Question

Quizplus · Accepted Answer

The researchers expected all five genes required for galactose catabolism to be part of an operon, as this is a common bacterial genetic arrangement. However, they did not find this to be the case, suggesting that eukaryotic gene regulation is more complex than that of bacteria.

Twenty-Five Years Ago,when Oshima and Colleagues Discovered That a Mutation