How do chromatin-remodeling complexes recognize the genes they should act on?
A)Chromatin-remodeling complexes are activated by specific extracellular signals that direct them to particular genes.
B)Chromatin-remodeling complexes recognize specific promoters when they are phosphorylated,methylated,or acetylated.
C)Chromatin-remodeling complexes recognize specific transcription factors bound to regulatory sequences of DNA.
D)Chromatin-remodeling complexes bind to the basal transcription complex.

Question

Quizplus · Accepted Answer

Chromatin-remodeling complexes recognize specific transcription factors bound to regulatory sequences of DNA. Transcription factors bind to specific DNA sequences called enhancers or silencers, which then recruit chromatin-remodeling complexes to either activate or repress gene expression. The chromatin-remodeling complexes can then modify the DNA and histone proteins to either open up or compact the chromatin structure, making the DNA more or less accessible to the transcriptional machinery. Promoter modifications may also play a role in directing chromatin-remodeling complexes, but the primary recognition signals are transcription factors bound to specific DNA regulatory elements.

How Do Chromatin-Remodeling Complexes Recognize the Genes They Should Act