Why does a person who has a deletion of the coding regions for five genes on one chromosome 15 have some manifestations or overt problems?
A)The deletions occurred in an autosome and not in a sex chromosome.
B)He or she has only one copy of the gene alleles, which results in reduced function.
C)The overall expression of the deleted areas is the same as if trisomy 15 were present.
D)The deleted areas are introns rather than exons; thus, no compensation occurred on the homologous chromosome.

Question

Quizplus · Accepted Answer

Although the chromosome is present, five gene alleles are missing. Thus, the production of proteins coded for by those alleles occurs solely as a result of the expression of those alleles on the normal chromosome. With only one allele active for these five genes, the person would produce lower amounts of the gene products.

Why Does a Person Who Has a Deletion of the Coding