Which type of testing is most commonly used to diagnose sickle cell disease?

Question

Quizplus · Accepted Answer

Genetic mutation testing is not used to diagnose SCD. It is diagnosed based on the large percentage of hemoglobin S (HbS) seen on electrophoresis. A person who has SCD usually has 80% to 90% HbS, and a person with sickle cell trait usually has less than 40% HbS. Although hemoglobin and hematocrit levels may be abnormal, they alone are not diagnostic for sickle cell disease. Sweat chloride levels are abnormal in people with cystic fibrosis and normal in people with sickle cell disease.

Which Type of Testing Is Most Commonly Used to Diagnose