Which type of parent compound must undergo first-phase metabolism to produce the intended response after it enters the body?
A)A prodrug
B)An active metabolite
C)An inactive metabolite
D)A sustained-released drug

Question

Quizplus · Accepted Answer

A prodrug is an inactive parent compound that must undergo first-phase metabolism to become an active drug that is capable of inducing an intended response. A sustained-release drug can be an active compound without first-phase metabolism, but the drug formulation allows slow and continuous release of the drug from its tablet or capsule. A parent compound is the actual drug as it enters the body and is not a metabolite.

Which Type of Parent Compound Must Undergo First-Phase Metabolism to Produce