Question 1

Distinguish among the following: endocytosis,pinocytosis,and phagocytosis.

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Question 2

Coated vesicles known as ________ are thought to potentially be associated with cholesterol uptake and/or have a role in signal transduction.

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Question 3

________ act as proton pumps and keep the internal proton concentration of lysosomes high.

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Question 4

________ is the molecule associated with receptor-mediated endocytosis that "coats" the vesicle until it is released.

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Question 5

V-________ and t-________ mediate final docking between target and vesicle.

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Question 6

________ is the organelle associated with the functions of steroid biosynthesis,carbohydrate metabolism,and drug detoxification.

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Question 7

Describe how Botox can be used in the treatment of wrinkles and muscle spasms at low concentrations.

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Question 8

If you were wanting to synthesize a particular protein in plants that allowed it to accumulate within the plant vacuole,how would you design your chimeric protein to concentrate within this vacuole? What features of the plant vacuole are unique?

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Question 9

The investigation of the movement of proteins and lipids to their appropriate location within a cell is known as ________.

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Question 10

Exocytosis is stimulated by regional increases in ________ concentration.

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Question 11

A ________ is a short sequence of amino acids that targets a protein for translation across the endoplasmic reticulum.

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Question 12

The ________ is the organelle involved in the posttranslational modification of proteins and sorting of proteins to various intracellular and extracellular compartments.

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Question 13

Design an experiment that will allow you to follow a protein from the endoplasmic reticulum,Golgi complex,and secretion vesicles to the outside of the cell.How will this differ if the protein is localized within lysosomes?

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Question 14

A ________ is the organelle that fuses with endosomes and supplies hydrolytic enzymes necessary for the digestion of the materials within the endosome.

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Question 15

The chronic use of the ________ class of drugs can result in decreased effectiveness of antibiotics,anticoagulants,and steroids.

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Question 16

________ are proteins associated with clathrin-coated vesicles that are involved in the binding of vesicles to specific receptors.

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Question 17

Peroxisomes and the smooth endoplasmic reticulum are both organelles associated with the detoxification of harmful substances.How do these two organelles differ with regard to this process?

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Question 18

Match between columns
                        Premises: presence of acid hydrolases
test for the TCA cycle enzymes
test for catalase activity
test for the presence of cytochromes
look for fractions that are green
ribulose bisphosphatase activity is present
hydroxylation of compounds including phenobarbital

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Question 19

Match between columns
                        Premises: tethering protein
smooth endoplasmic reticulum
mannose-6-phosphate
glyoxysomes
shuttle vesicle
Golgi apparatus
lysosomes
transition vesicle
peroxisomes
secretory vesicle

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Quiz 12: The Endomembrane System and Peroxisomes