Glucagon can induce gene transcription in the liver.How?
A) It is translocated to the nucleus, where it binds to response elements in the regulatory sequences of the genes.
B) It triggers cAMP formation, and cAMP activates genes by binding to the catabolite activator protein.
C) It releases calcium from the ER, which activates protein kinase C in the nucleus.
D) It causes phosphorylation of nuclear transcription factors by protein kinase A.
E) It induces the formation of the second messenger IP3, which activates transcription by binding to nuclear transcription factors.
Correct Answer:
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Q1: The second messenger cyclic adenosine monophosphate (cAMP)
Q2: Some hormones act by triggering the release
Q4: You work as research director for a
Q5: The actions of insulin are initiated by:
A)Phosphorylation
Q6: Many cytoplasmic enzymes become activated in response
Q7: A linkage study has found that there
Q8: One important feature of the insulin receptor
Q9: IP₃ is a second messenger of many
Q10: cAMP stimulates hormone production and cell proliferation
Q11: There is much overlap of the intracellular
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