Question 1

Ulcerative colitis produces inflammation in the upper layers of the lining of the _____ and colon,whereas Crohn's disease produces inflammation deep in the _____.

Accepted Answer

Ulcerative colitis produces inflammation in the upper layers of the lining of the small intestine and colon,whereas Crohn's disease produces inflammation deep in the intestinal wall.

Question 2

Azathioprine,6-mercaptopurine,and methotrexate are classified as antimetabolites.They are used in the treatment of Crohn's disease to ______.

Accepted Answer

Azathioprine,6-mercaptopurine,and methotrexate are classified as antimetabolites.They are used in the treatment of Crohn's disease to induce remission.

Question 3

Aminosalicylates work via what mechanism?

Accepted Answer

Sulfasalazine (sulfapyridine + 5-ASA)and olsalazine (two 5-ASA molecules)are prodrugs.Bacteria in the colon metabolize the drugs and release the active metabolite (5-ASA).Mesalamine and mesalazine are coated with a pH-dependent resin.The 5-ASA is released in the pH of the distal ileum (mesalamine)and proximal ileum (mesalazine)rather than the colon.

Question 4

How are the patients who have irritable bowel syndrome,ulcerative colitis,or Crohn's disease tested to confirm diagnosis?

Accepted Answer

Irritable bowel syndrome,ulcerative colitis,and Crohn's disease can be diagnosed by testing stool samples,taking radiographs,and performing a colonoscopy.

Question 5

Which disease affects men and women equally?

Accepted Answer

Ulcerative colitis tends to run in families but,unlike irritable bowel disease,it affects men and women equally.

Question 6

Which drug is used to control diarrhea caused by severe IBS and is available only from health care providers who participate in a special prescribing program?

Accepted Answer

Alosetron is available only from health care providers who participate in a special prescribing program.

Question 7

Which of the following diseases is treated by administering serotonin receptor antagonists (5-HT₃ and 5-HT₄),antidiarrheals,laxatives,fiber supplements,and anticholinergics?

Accepted Answer

Irritable bowel syndrome is treated by administering serotonin receptor antagonists (5-HT₃ and 5-HT₄),antidiarrheals,laxatives,fiber supplements,and anticholinergics.

Question 8

MATCHING
Match the following trade and generic drug names.
a.Imodium
b.Remicade
c.Asacol
d.Zelnorm
e.Fibercon
-loperamide

Accepted Answer

The answer of MATCHING
Match the following trade and generic drug...

Question 9

MATCHING
Match the following trade and generic drug names.
a.Imodium
b.Remicade
c.Asacol
d.Zelnorm
e.Fibercon
-infliximab

Accepted Answer

The answer of MATCHING
Match the following trade and generic drug...

Question 10

The only FDA-approved anticholinergic drugs used in the treatment of irritable bowel syndrome when diarrhea is the primary symptom are _____.

Accepted Answer

Anticholinergic drugs are used in the treatment of irritable bowel syndrome when diarrhea is the primary symptom.Atropine and dicyclomine are the only FDA-approved agents for the treatment of IBS.

Question 11

Which diseases are conditions that are linked to inflammation of gastrointestinal tract?

Accepted Answer

Irritable bowel syndrome,ulcerative colitis,and Crohn's disease are conditions that are linked to inflammation of gastrointestinal tract.

Question 12

Patients who have Crohn's disease may develop _____,which form when an ulcer tunnels from the site of origin to surrounding tissues.

Accepted Answer

Patients who have Crohn's disease may develop fistulas.A fistula forms when an ulcer tunnels from the site of origin to surrounding tissues.

Question 13

An immunomodulator that has been approved for the treatment of Crohn's disease is _____.

Accepted Answer

Infliximab is an immunomodulator that has been approved for the treatment of Crohn's disease.

Question 14

What are three common symptoms of irritable bowel syndrome,ulcerative colitis,and Crohn's disease?

Accepted Answer

Irritable bowel syndrome,ulcerative colitis,and Crohn's disease are conditions that are linked to inflammation of gastrointestinal tract.Many of the symptoms are similar (i.e. ,abdominal pain and diarrhea)

Question 15

The laxatives of choice for treating the symptoms of irritable bowel syndrome are _____.

Accepted Answer

Bulk-forming laxative and fiber supplements are administered to relieve constipation and diarrhea.They are the laxative of choice for treating the symptoms of irritable bowel syndrome.

Question 16

MATCHING
Match the following trade and generic drug names.
a.Imodium
b.Remicade
c.Asacol
d.Zelnorm
e.Fibercon
-polycarbophil

Accepted Answer

The answer of MATCHING
Match the following trade and generic drug...

Question 17

Which of the following is not an opioid antidiarrheal administered to control watery and frequent stools and prescribed for the treatment of diarrhea?

Accepted Answer

Opioid antidiarrheals are administered to control watery and frequent stools.Opioid antidiarrheals prescribed for the treatment of diarrhea are difenoxin,diphenoxylate,and loperamide.

Question 18

MATCHING
Match the following trade and generic drug names.
a.Imodium
b.Remicade
c.Asacol
d.Zelnorm
e.Fibercon
-tegaserod

Accepted Answer

The answer of MATCHING
Match the following trade and generic drug...

Question 19

MATCHING
Match the following trade and generic drug names.
a.Imodium
b.Remicade
c.Asacol
d.Zelnorm
e.Fibercon
-mesalamine

Accepted Answer

The answer of MATCHING
Match the following trade and generic drug...

Quiz 27: Treatment of Irritable Bowel Syndrome,ulcerative Colitis and Crohns Disease

Ulcerative colitis produces inflammation in the upper layers of the lining of the _ and colon,whereas Crohn's disease produces inflammation deep in the _.

Azathioprine,6-mercaptopurine,and methotrexate are classified as antimetabolites.They are used in the treatment of Crohn's disease to ______.

Aminosalicylates work via what mechanism?

How are the patients who have irritable bowel syndrome,ulcerative colitis,or Crohn's disease tested to confirm diagnosis?

Which disease affects men and women equally?

Which drug is used to control diarrhea caused by severe IBS and is available only from health care providers who participate in a special prescribing program?

Which of the following diseases is treated by administering serotonin receptor antagonists (5-HT₃ and 5-HT₄) ,antidiarrheals,laxatives,fiber supplements,and anticholinergics?

MATCHING Match the following trade and generic drug names. a.Imodium b.Remicade c.Asacol d.Zelnorm e.Fibercon -loperamide

MATCHING Match the following trade and generic drug names. a.Imodium b.Remicade c.Asacol d.Zelnorm e.Fibercon -infliximab

The only FDA-approved anticholinergic drugs used in the treatment of irritable bowel syndrome when diarrhea is the primary symptom are _____.

Which diseases are conditions that are linked to inflammation of gastrointestinal tract?

Patients who have Crohn's disease may develop _____,which form when an ulcer tunnels from the site of origin to surrounding tissues.

An immunomodulator that has been approved for the treatment of Crohn's disease is _____.

What are three common symptoms of irritable bowel syndrome,ulcerative colitis,and Crohn's disease?

The laxatives of choice for treating the symptoms of irritable bowel syndrome are _____.

MATCHING Match the following trade and generic drug names. a.Imodium b.Remicade c.Asacol d.Zelnorm e.Fibercon -polycarbophil

Which of the following is not an opioid antidiarrheal administered to control watery and frequent stools and prescribed for the treatment of diarrhea?

MATCHING Match the following trade and generic drug names. a.Imodium b.Remicade c.Asacol d.Zelnorm e.Fibercon -tegaserod

MATCHING Match the following trade and generic drug names. a.Imodium b.Remicade c.Asacol d.Zelnorm e.Fibercon -mesalamine