P63 (also known as Tumor protein p73-like [TP73L])mutations affect development of the skin in a spectrum of syndromes that include ectrodactyly ectodermal dysplasia-cleft lip/palate.Which cell layer of the skin expresses P63?

Question

Quizplus · Accepted Answer

P63 is expressed in the basal layer of the epidermis, which is also known as the stratum germinativum. This layer contains the stem cells that give rise to the differentiated cells of the upper layers of the skin. Mutations in P63 can affect the development of this layer and result in various skin disorders.

P63 (Also Known as Tumor Protein P73-Like [TP73L])mutations Affect Development