Mutations in particular genes can cause or increase the risk of specific congenital anomalies of the urogenital system.Which gene when mutated is most likely to be responsible for congenital bilateral aplasia of the vas deferens?

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Congenital bilateral aplasia of the vas deferens (CBAVD) is most commonly caused by mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR). Mutations in this gene can also cause cystic fibrosis, a disease that affects multiple organ systems including the lungs, pancreas, and reproductive organs. Mutations in the other genes listed (AMH receptor, WT1, 5α F.-reductase, PDK1) are associated with different urogenital anomalies, but not CBAVD.

Mutations in Particular Genes Can Cause or Increase the Risk