Two hypothetical small volume nebulizers,A and B,have the following specifications from the manufacturer:
Which nebulizer would be best to use to treat the lower respiratory tract?

Question

Two hypothetical small volume nebulizers,A and B,have the following specifications from the manufacturer: 
Which nebulizer would be best to use to treat the lower respiratory tract?

Quizplus · Accepted Answer

Although nebulizer B has a smaller CMD than nebulizer A,nebulizer A produces particles whose mass centers within a lower range and so would be the better nebulizer with which to treat the lower respiratory tract.A major factor in lung penetration by aerosols is particle size,which is best characterized by the mass median aerodynamic diameter (MMAD)for inhaled drugs,because particle mass is a function of the third power of the particle radius.Nebulizer A produces particles whose mass centers within a lower size range (1 to 5 µm),and would be the better nebulizer for treatment of the lower respiratory tract.

Two Hypothetical Small Volume Nebulizers,A and B,have the Following Specifications