All metered dose inhalers (MDIs)are powered by which propellant?

Question

Quizplus · Accepted Answer

In agreement with the Montreal Protocol,all MDIs in the United States ceased use of CFCs by the end of 2008.Soy lecithin is not a propellant used to power an MDI;it is a surfactant used to prevent aggregation of drug particles and to lubricate the valve mechanism.HFAs are the new propellant of choice and became a requirement in 2008.Oleic acid,similar to soy lecithin,is a surfactant used to prevent the aggregation of drug particles and to lubricate the valve mechanism.CFCs and HFAs are the two types of propellants used with pressurized MDIs (pMDIs).Although CFC propellants used with pMDIs to create an aerosol were blends of liquefied gas (CFCs)in the past,because 1 CFC molecule can destroy 100,000 molecules of stratospheric ozone,the U.S.Food and Drug Administration (FDA)banned the use of CFC pMDIs.Hydrofluorocarbons (HFCs),also termed HFAs,have been identified as propellants that are nontoxic to the atmosphere and to the patient and that have properties suitable for MDI aerosol generation.

All Metered Dose Inhalers (MDIs)are Powered by Which Propellant