A patient has numerous spherocytes noted on the blood smear.Which of the following will confirm a diagnosis of autoimmune hemolytic anemia.

Question

Quizplus · Accepted Answer

A positive direct antiglobulin test (also known as Coombs test) is used to detect antibodies and/or complement proteins attached to the surface of the red blood cells, which is a hallmark of autoimmune hemolytic anemia. The other options are not specific to this diagnosis - a low MCV can indicate iron deficiency anemia, banding in the A1, A2, and F regions suggests a bone marrow disorder, and normal unconjugated bilirubin can be seen in many different types of anemia.

A Patient Has Numerous Spherocytes Noted on the Blood Smear