The technologist is reviewing a blood smear of a patient.He notices many immature blasts exhibiting prominent cytoplasmic basophilia and vacuolization.Cytogenetic analysis performed on this patient identified a translocation between chromosomes 8 and 14.Based on this information, what is the patient most likely suffering from?

Question

Quizplus · Accepted Answer

The presence of immature blasts with prominent cytoplasmic basophilia and vacuolization, along with a translocation involving chromosomes 8 and 14, is highly suggestive of ALL in the Burkitt type. Precursor B cell ALL (choice A) is also a possibility, but the chromosomal abnormality seen here is more specific to the Burkitt type. Choice B (Precursor T cell ALL) and choice D (Cannot be determined based on the information given) are not supported by the information given.

The Technologist Is Reviewing a Blood Smear of a Patient